Research Histopathology
The Research Histopathology Core consists of three sub-cores located at strategically placed sites: The Sterling Forest Research Histopathology core (RHC), the Manhattan RHC, and the Immunochemistry core IHC.
The Manhattan RHC, located in the heart of the Pathology Department, provides histopathology services for both research human tissues and for animal model studies. The Core processes fixed human tissues (for IRB-approved studies), generating stained or unstained slides. We also have abundant expertise in animal models, especially mouse histopathology. Our highly trained personnel provide necropsy, dissection and tissue processing services, as well as frozen sections and customized services. As part of the educational mission of the Department, we also provide one-on-one consultation and training for graduate students, post-docs, and faculty on the use of Core equipment and the characterization of mouse models. Although there are commercial and academic histology services available, none can provide the same level of service, rapid turn-around time, or serve the educational mission of the Department as well as our on-site Core.
Location: MSB 126. Hours of Operation: 9:00 am to 5:00 pm
Core Lab services:Histopathologic services include tissue preparation, processing, embedding, sectioning and histochemical staining for paraffin and cryo-embedded tissues from IACUC-approved animal studies conducted on the Manhattan campus.
Microtomy Services
Basic microtomy services for paraffin-embedded human specimens obtained through IRB-approved sources are available.
Available Equipment: Automated Leica Tissue Processor- TP1050; Leica Embedding Center –EG 1160; Leica Microtome – RM2155; Reichert-Jung Microtome – 2050; Micron Cryostat – HM500OM; Leica autostainer XL; Fume hood equipped with staining racks for manual de-paraffinization and staining; Leica Laser Micro-Dissection System with Fluorescence, recently upgraded to a LMD6000 model with a motorized stage and touch screen capabilities.
Custom Services: New services can be provided and existing services varied according to the needs of the research community.