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Research and Clinical Interests

Dr. Nonaka serves in the surgical pathology section, and is chief of the thoracic pathology and endocrine pathology service. He is also a member of the genitourinary pathology service. Dr. Nonaka's academic activities include diagnostic pathology and translational research on neoplasia of the thorax, thyroid glands, and soft tissue, and malignant melanomas.

Selected Publications

Nonaka D, Chiriboga L, Rubin BP. Sox10: a pan-schwannian and melanocytic marker. Am J Surg Pathol. 2008 Sep;32(9):1291-8. Cited in Pubmed; PMID 18636017.

Nonaka D, Tang Y, Chiriboga L, Rivera M, Ghossein R. Diagnostic utility of thyroid transcription factors Pax8 and TTF-2 (FoxE1) in thyroid epithelial neoplasms. Mod Pathol. 2008 Feb;21(2):192-200. Epub 2007 Dec 14. Cited in Pubmed; PMID 18084247. doi: 10.1038/modpathol.3801002.

Nonaka D, Rodriguez J, Rosai J. Extraneural hemangioblastoma: a report of five cases. American Journal of Surgical Pathology. 2007 Oct;31(10):1545-51. Cited in Pubmed; PMID 17895756.

Baratti D, Kusamura S, Nonaka D, Oliva GD, Laterza B, Deraco M. Multicystic and Well-differentiated Papillary Peritoneal Mesothelioma Treated by Surgical Cytoreduction and Hyperthermic Intra-peritoneal Chemotherapy (HIPEC). Annals of Surgical Oncology. 2007 Oct;14(10):2790-97. Cited in Pubmed; PMID 17661150.

Nonaka D, Henley JD, Chiriboga L, Yee H. Diagnostic utility of thymic epithelial markers CD205 (DEC205) and Foxn1 in thymic epithelial neoplasms. American Journal of Surgical Pathology. 2007 Jul;31(7):1038-44. Cited in Pubmed; PMID 17592270.

Anichini A, Mortarini R, Nonaka D, Molla A, Vegetti C, Montaldi E, Wang X, Ferrone S. Association of antigen processing machinery and HLA antigen phenotype pf melanoma cells with survival in AJCC Stage III and IV melanoma. Cancer Research. 2006 Jun;25(24):6405-11. Cited in Pubmed; PMID 16778219.

Sensi M, Nicolini G, Petti C, Bersani I, Lozupone F, Molla A, Vegetti C, Nonaka D, Mortarini R, Parmiani G, Fais S, Anichini A. Mutually exclusive NRASQ61R and BRAFV600E mutations at the single cell level in the same human melanoma. Oncogene. 2006;25(24):3357-64. Cited in Pubmed; PMID 16462768.

Nonaka D, Kusamura S, Baratti D, Casali P, Rosai J, Younan R, Deraco M. Diffuse malignant mesothelioma of the peritoneum: a clinicopathologic study of 35 cases treated locoregionally at a single institution. Cancer. 2005 Nov;104(10):281-8. Cited in Pubmed; PMID 16206294.

Nonaka D, Birbe R, Rosai J. So-called inflammatory myofibroblastic tumour: a proliferative lesion of fibroblastic reticulum cells? Histopathology. 2005 Jun;46(6):604-13. Cited in Pubmed; PMID 15910591.

Nonaka D, Rodriguez J, Rollo JL, Rosai J. Undifferentiated large cell carcinoma of the thymus with Castleman’s disease-like reaction: a distinctive type of thymic neoplasm characterized by an indolent behavior. American Journal of Surgical Pathology. 2005 Apr;29(4):490-5. Cited in Pubmed; PMID 15767803.

Mortarini R, Scarito A, Nonaka D, Zanon M, Bersani I, Montaldi E, Pennacchioli E, Patuzzo R, Santinami M, Anichini A. Constitutive expression and costimulatory function of LIGHT/TNFSF14 on human melanoma cells and melanoma-derived microvesicles. Cancer Research. 2005 Apr;65(8):3428-36. Cited in Pubmed; PMID 15833878.

Nonaka D, Fabbri A, Roz L, Mariani L, Vecchione A, Moore GW, Tavecchio L, Croce CM, Sozzi G. Reduced FEZ1/LZTS1 Expression and Outcome Prediction in Lung Cancer. Cancer Research. 2005 Feb;65(4):1207-12. Cited in Pubmed; PMID 15735004.

Nonaka D, Klimstra D, Rosai J. Thymic mucoepidermoid carcinomas: a clinicopathologic study of ten cases. American Journal of Surgical Pathology. 2004 Nov;28(11):1526-31. Cited in Pubmed; PMID 15489658.

Leitao MM, Soslow RA, Nonaka D, Olshen AB, Aghajanian C, Sabbatini P, Dupont J, Hensley M, Sonoda Y, Barakat RR, Anderson S. Tissue microarray immunohistochemical expression of estrogen, progesterone, and androgen receptors in uterine leiomyomata and leiomyosarcoma. Cancer. 2004 Sep;101(6):1455-62. Cited in Pubmed; PMID 15316901.

Nonaka D, Rosai J, Spagnolo D, Fiaccavento S, Bisceglia M. Cylindroma of the breast of skin adnexal type: a study of four cases. American Journal of Surgical Pathology. 2004 Aug;28(8):1070-5. Cited in Pubmed; PMID 15252315.

Selected Books

Wang BY, Zagzag D, Nonaka D. Chapter 12: Tumors of the Central Nervous System. In: Barnes L, editor. Surgical Pathology of the Head and Neck. 3rd edition. New York: Taylor & Francis Group; 2008. pp. 669-772.

Nonaka D, Zagzag D, Wang B. Tumors of the Nervous System. Chapter 15. In: Barnes L, editor. Surgical Pathology of the Head and Neck. New York: M. Dekker; 2001.

Organizational Associations

United States and Canadian Academy of Pathology (USCAP); American Society for Clinical Pathology (ASCP); College of American Pathologists (CAP); North American Society for Head and Neck Pathology; Pulmonary Pathology Society

Selected Awards

2009 Attending of the Year in Anatomic Pathology Award

Hospital Affiliations

Tisch Hospital