Research and Clinical Interests

Dr. Mittal's research has focused on gynecologic pathology. Areas of interest include uterine, cervical, ovarian, and tubal carcinomas, uterine leiomyosarcoma, and placental pathology. Current work includes 1) Description and prognostic significance of an intermediate stage (Adenocarcinoma-in-situ) between complex atypical endometrial hyperplasia and endometrial adenocarcinoma. 2) Morphologic and genetic evidence for origin of uterine leiomyosarcomas from precursor benign looking lesions.

Selected Publications

Mittal K, Soslow R, McCluggage W. Application of Immunohistochemistry to Gynecologic Pathology [invited review article]. Arch Path Lab Med. 2008 Mar;132(3):402-23. Cited in Pubmed; PMID 18318583.

Mittal K, Da Costa D. Endometrial hyperplasia and carcinoma in endometrial polyps: clinicopathologic and follow-up findings. Int J Gynecol Pathol. 2008 Jan;27(1):45-8:45-8. Cited in Pubmed; PMID 18156974.

Mittal K, Joutovsky A. Areas with Benign Morphologic and Immunohistochemical features are associated with some Uterine Leiomyosarcomas. Gynecol Oncol. 2007 Feb;104(2):362-5. Cited in Pubmed; PMID 17011615.

Wei JJ, Zhang XM, Chiriboga L, Yee H, Mittal K. Large Uterine Leiomyomata: Spatial Differences in Biological Activity. Fertil Steril. 2006;85:179-87. Cited in Pubmed; PMID 16412751.

Wei JJ, Chiriboga L, Arslan AA, Melamed J, Yee H, Mittal K. Ethnic Differences in Expression of the Dysregulated Proteins in Uterine Leiomyomata. Human Reproduction. 2006;21:57-67. Cited in Pubmed; PMID 16172143.

Mittal K. Differences in mitotic activity may explain observed differences in HIF-1 alpha response in cancers and stroma. PLoS Med. 2006;3(8):e370.

Wei JJ, Chiriboga L, Mittal K. Expression profile of the tumorigenic factors in association with tumor size and sex steroid hormone status in uterine leiomyomata. Fertil Steril. 2005;84:474-84. Cited in Pubmed; PMID 16084893.

Wei J, Chiriboga L, Mizuguchi M, Yee H, Mittal K. Expression profile of Tuberin and Some Potential Tumorigenic Factors in 60 Patients with Uterine Leiomyomata. Mod Pathol. 2005;18:179-188. Cited in Pubmed; PMID 15467714.

Popiolek D, Ventura K, Mittal K. Distinction of low-grade squamous intraepithelial lesions from high-grade squamous intraepithelial lesions based on quantitative analysis of proliferative activity. Oncol Rep. 2004;11:687-91. Cited in Pubmed; PMID 14767523.

Ventura KC, Popiolek D, Mittal K. Endometrial Adenocarcinoma In-Situ in Complex Atypical Hyperplasia: Correlation with Findings in Subsequent Hysterectomy Specimen. Int J Surg Path. 2004;12:225-230. Cited in Pubmed; PMID 15306934.

Mittal K. The nine lives of beta-Catenin [editorial]. Human Pathology. 2004;35:647-8.

Yin H, Mittal K. Incidental findings in uterine prolapse specimen: frequency and implications. Int J Gynecol Pathol. 2004;23:26-28. Cited in Pubmed; PMID 14668546.

Qiu W, Mittal K. Comparison of Morphologic and Immunostaining Patterns of Cervical Microglandular Hyperplasia with Mucinous Adenocarcinoma of the Endometrium. Int J Gynecol Pathol. 2003;22:261-5. Cited in Pubmed; PMID 12819393.

Levine PH, Elgert PA, Mittal K. False positive squamous cell carcinoma in cervical smears: cytologic-histologic correlation in 19 cases. Diagn Cytopathol. 2003;28:23-27. Cited in Pubmed; PMID 12508178.

Selected Books

Mittal KR, Zeleniuch Jacqotte A, Cooper J, Demopoulos RI. Contralateral ovary in unilateral ovarian carcinoma: A search for pre neoplastic lesions. In: Year Book of Obstetrics and Gynecology. St. Louis: Mosby Year Book Inc; 1994.

Mittal KR, Barwick KW. Endometrial adenocarcinoma involving adenomyosis without true myometrial invasion is characterized by frequent preceding estrogen therapy, low histologic grades and excellent prognosis. In: Year Book of Obstetrics and Gynecology. St. Louis: Mosby Year Book Inc; 1994.

Demopoulos RI, Mittal KR. Anatomy, Histology and Physiology. In: Altchek A, Deligdisch L, editors. Clinical Perspectives in Obstetrics and Gynecology: The Uterus. New York: Springer-Verlag; 1991.

Organizational Associations

United States and Canadian Academy of Pathology; International Association of Gynecologic Pathologists; Editorial Board, International Journal of Gynecologic Pathology; Editorial Board, Human Pathology; Editorial Board, Gynecologic Oncology; Scientific Abstract Review Committee, United States and Canadian Academy of Pathology

Hospital Affiliations

Tisch Hospital
Bellevue Hospital