Juan J. Lafaille, Ph.D.
Associate Professor of Pathology and Medicine
Experimental Pathology, Immunology, Pathobiology / Pathogenesis of autoimmune and allergic diseases, regulatory T cells
juan.lafaille@med.nyu.edu, (212) 263 1489
Fax: (212) 263 5711
540 First Avenue, SKI 2nd Floor Lab 7, New York, NY 10016
Selected Publications
Curotto de Lafaille MA, Kutchukhidze N, Shen S, Ding Y, Yee H, and Lafaille JJ. Adaptive Foxp3+ Regulatory T cell-dependent and -independent control of allergic inflammation. Immunity. 2008 Jul 18;29:114-26. Epub 2008 Jul 10. Cited in Pubmed; PMID 18617425. doi: 10.1016/j.immuni.2008.05.010.
Ding Y, Shen S, Lino AC, Curotto de Lafaille MA, Lafaille JJ. Beta-catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cells. Nat Med. 2008 Feb;14(2):162-9. Epub 2008 Feb 3. Cited in Pubmed; PMID 18246080. doi: 10.1038/nm1707.
Maraver A, Tadokoro CE, Badura ML, Shen J, Serrano M, Lafaille JJ. Effect of presenilins in the apoptosis of thymocytes and homeostasis of CD8+ T cells. Blood. 2007 Nov 1;110:3218-25. Epub 2007 Nov 1. Cited in Pubmed; PMID 17626841.
Erazo A, Kutchukhidze N, Leung M, Christ AP, Urban JF Jr, Curotto de Lafaille MA, Lafaille JJ. Unique maturation program of the IgE response in vivo. Immunity. 2007 Feb;26(2):191-203. Cited in Pubmed; PMID 17292640.
Ivanov II, McKenzie BS, Zhou L, Tadokoro CE, Lepelley A, Lafaille JJ, Cua DJ, Littman DR. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell. 2006 Sep 22;126(6):1121-33. Cited in Pubmed; PMID 16990136.
Tadokoro CE, G. Shakhar G, S. Shen S, Y. Ding Y, A.C. Lino AC, Maraver A, Lafaille JJ, Dustin ML. Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo. J Exp Med. 2006;203:505-511. Cited in Pubmed; PMID 16533880.
Marcondes MC, Furtado GC, Wensky A, Curotto de Lafaille MA, Fox HS, Lafaille JJ. Immune regulatory mechanisms influence early pathology in spinal cord injury and in spontaneous autoimmune encephalomyelitis. Am J Pathol. 2005 Jun;166(6):1749–60. Cited in Pubmed; PMID 15920160.
Wensky AK, Furtado GC, Garibaldi Marconedes MC, Chen S, Manfra D, Lira SA, Zazzag D, Lafaille JJ. IFN-gamma determines distinct clinical outcomes in autoimmune encephalomyelitis. Immunol. 2005 Feb 1;174(3):1416-23. Cited in Pubmed; PMID 15661899.
Yan SS; Wu ZY; Zhang HP; Furtado G; Chen X; Yan SF; Schmidt AM; Brown C; Stern A; Lafaille J; Chess L; Stern DM; Jiang H. Suppression of experimental autoimmune encephalomyelitis by selective blockade of encephalitogenic T-cell infiltration of the central nervous system. Nat Med. 2003;9:287-93. Cited in Pubmed; PMID 12598893.
