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Selected Publications

Chen TM, Chen CA, Hsieh CY, Chang DY, Chen YH, Defendi V. The state of p53 in primary human cervical carcinomas and its effects in human papillomavirus-immortalized human cervical cells. Oncogene. 1993 Jun;8(6):1511–8. Cited in Pubmed; PMID 8389030.

Chen TM, Pecoraro G, Defendi V. Genetic analysis of in vitro progression of human papillomavirus-transfected human cervical cells. Cancer Res. 1993 Mar 1;53(5):1167–71. Cited in Pubmed; PMID 8382557.

Chen TM, Defendi V. Functional interaction of p53 with HPV18 E6, c-myc and H-ras in 3T3 cells. Oncogene. 1992 Aug;7(8):1541–7. Cited in Pubmed; PMID 1321402.

Morgan DM, Pecoraro G, Rosenberg I, Defendi V. Transformation by human papillomavirus type 16 (HPV16) DNA but not HPV6b DNA is enhanced by addition of the human cytomegalovirus enhancer. Virology. 1992 Aug;189(2):687–94. Cited in Pubmed; PMID 1322595.

Pecoraro G, Lee M, Morgan D, Defendi V. Evolution of in vitro transformation and tumorigenesis of HPV16 and HPV18 immortalized primary cervical epithelial cells. Am J Pathol. 1991 Jan;138(1):1–8. Cited in Pubmed; PMID 1846261.

Morgan D, Pecoraro G, Rosenberg I, Defendi V. Human papillomavirus type 6b DNA required for initiation but not maintenance of transformation of C127 mouse cells. J Virol. 1990 Mar;64(3):969–76. Cited in Pubmed; PMID 2154622.

Morris AE, Steinberg ML, Le JY, Defendi V. Isolation of novel cDNA transformation markers from SV40-transformed human keratinocytes. Exp Cell Res. 1989 Jun;182(2):461–72. Cited in Pubmed; PMID 2470605.

Pecoraro G, Morgan D, Defendi V. Differential effects of human papillomavirus type 6, 16, and 18 DNAs on immortalization and transformation of human cervical epithelial cells. Proc Natl Acad Sci U S A. 1989 Jan;86(2):563–7. Cited in Pubmed; PMID 2463631.

Le JY, Defendi V. Viral-cellular junction fragment from a human papillomavirus type 16-positive tumor is competent in transformation of NIH 3T3 cells. J Virol. 1988 Nov;62(11):4420–6. Cited in Pubmed; PMID 2845153.

Morgan D, Pecoraro G, Rosenberg I, Defendi V. Transformation of C127 mouse fibroblasts by human papillomavirus 16. Cancer Res. 1988 May 1;48(9):2505–11. Cited in Pubmed; PMID 2833348.

Mallon RG, Wojciechowicz D, Defendi V. DNA-binding activity of papillomavirus proteins. J Virol. 1987 May;61(5):1655–60. Cited in Pubmed; PMID 3033292.

Morris A, Steinberg ML, Defendi V. Keratin gene expression in simian virus 40-transformed human keratinocytes. Proc Natl Acad Sci U S A. 1985 Dec;82(24):8498-502. Cited in Pubmed; PMID 2417222.

Steinberg ML, Defendi V. Altered patterns of keratin synthesis in human epidermal keratinocytes transformed by SV40. J Cell Physiol. 1985 Apr;123(1):117–25. Cited in Pubmed; PMID 2579084.

Edelman B, Steinberg ML, Defendi V. Changes in fibronectin synthesis and binding distribution in SV40-transformed human keratinocytes. Int J Cancer. 1985 Feb 15;35(2):219–25. Cited in Pubmed; PMID 2579033.

Selected Books

Caroll RB, Defendi V. Viral Antigens in the Cell Nucleus. In: Hnilica LS, editor. Chromosomal nonhistone proteins. Vol. II. Immunology. Boca Raton, FL: CRC Press; 1983. pp. 189–248.

Defendi V, editor. Heterospecific Genome Interaction. The Wistar Institute Symposium Monograph, no. 9. Philadelphia: Wistar Institute Press; 1969.

Defendi V, Stoker M, editors. Growth Regulating Substances of Animal Cells in Culture. The Wistar Institute Symposium Monograph, no. 7. Philadelphia: Wistar Institute Press; 1967.

Defendi V, editor. Methodological approaches to the study of leukemias. The Wistar Institute Symposium Monograph, no. 4. Philadelphia: Wistar Institute Press; 1965.

Defendi V, editor. The Thymus. The Wistar Institute Symposium Monograph, no. 2. Philadelphia: Wistar Institute Press; 1964.

Organizational Associations

American Society for Investigative Pathology; American Association for the Advancement of Science; American Association for Cancer Research; American Society for Microbiology; American Association of Immunology; The Harvey Society; Pluto Club; The Century Association

Selected Awards

Doctor, Honoris Causa, University of Helsinki, Finland
Knight of the White Rose, Republic of Finland
Honorary Alumnus New York University Medical School (2004)
Fellow, American Association for the Advancement of Science
Fellow, New York Academy of Science
Research Professor (lifetime), American Cancer Society
Mary Ellen and Gerald Ritter Chair of Oncology at NYU
Scholar, Leukemia Society of America
Fulbright Scholar
British Council Scholar Award
Crescenzi Award-Highest Academic Achievement
Lepetit Prize-Best Thesis