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Blas Frangione, M.D., Ph.D.
Alzheimer’s disease; dementia; stroke
Dr. Frangione is studying the relationship between protein misfolding (amyloid) and Alzheimer's disease and the mechanisms leading to dementia and/or stroke. His current lines of investigation include 1) the search for mutations in familial Alzheimer disease and non-Aβ amyloidosis; 2) their mechanism of protein aggregation and neuronal cell death; 3) the development of transgenic animals for therapeutic approaches and 4) the relation between chaperones (e.g. ApoE, J, etc) and amyloidogenesis.
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Over three hundred people are affiliated with the NYU Department of Pathology. The faculty is divided evenly between research and clinical science. These faculty members also supervise a wide range of graduate students, postdocs, and clinical fellows. In this they are supported by a dedicated core of staff and technicians.
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